RGD1561496 antibody, C1orf22 antibody, 2310050N11Rik antibody, ER degradation enhancing alpha-mannosidase like protein 3 antibody, ER degradation enhancer, mannosidase alpha-like 3 L homeolog antibody, ER degradation enhancer, mannosidase alpha-like 3 antibody, Edem3 antibody, EDEM3 antibody, edem3.L antibody, edem3 antibody
Background
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).Synonyms: C1orf22, ER degradation-enhancing alpha-mannosidase-like 3