DOC2A antibody (Middle Region)

Catalog No. ABIN951966

Product Details anti-DOC2A Antibody

Target: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Binding Specificity: AA 284-314, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOC2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human DOC2A (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 284-314 amino acids from the Central region of Human DOC2A

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DOC2A

Target: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Alternative Name: DOC2A (DOC2A Products)

Synonyms: DOC2A antibody, doc2-A antibody, Doc2 antibody, double C2 domain alpha antibody, double C2-like domains, alpha antibody, double C2, alpha antibody, DOC2A antibody, doc2a antibody, Doc2a antibody

Background: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes, these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.Synonyms: Doc2, Doc2-alpha, Double C2-like domain-containing protein alpha

Molecular Weight: 43959 Da

Gene ID: 8448

NCBI Accession: NP_003577

Pathways: Synaptic Vesicle Exocytosis