DENND1B antibody (N-Term)
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- Target See all DENND1B Antibodies
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
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Binding Specificity
- AA 46-76, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DENND1B antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognizes Human DENND1B (N-term).
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 46-76 amino acids from the N-terminal region of Human DENND1B. Genename: DENND1B
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DENND1B Primary Antibody
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anti-DENN/MADD Domain Containing 1B (DENND1B) (AA 39-68), (N-Term) antibody
DENND1B Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB28056 unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) (Center) antibodyDENND1B Reactivity: Human, Mouse WB, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) (AA 108-157) antibodyDENND1B Reactivity: Human, Rabbit, Cow, Dog WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) (AA 144-193) antibodyDENND1B Reactivity: Human, Mouse, Rabbit, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio), Bat, Chicken, Monkey, Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) antibodyDENND1B Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-DENN/MADD Domain Containing 1B (DENND1B) (AA 1-396) antibodyDENND1B Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS, 0.09 % (W/V) Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
- Alternative Name
- DENND1B (DENND1B Products)
- Background
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).Synonyms: C1orf218, Connecdenn 2, DENN domain-containing protein 1B, FAM31B
- Molecular Weight
- 48260 Da
- Gene ID
- 163486
- NCBI Accession
- NP_001182144
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