CENPH antibody (Middle Region)

Catalog No. ABIN951466

Product Details anti-CENPH Antibody

Target: CENPH (Centromere Protein H (CENPH))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPH antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CENPH.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human CENPH

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CENPH

Target: CENPH (Centromere Protein H (CENPH))

Alternative Name: CENP-H (CENPH Products)

Synonyms: 1700021I11Rik antibody, 2410018A12Rik antibody, 2610042E16Rik antibody, 2810046K12Rik antibody, AU044255 antibody, CENP-H antibody, ENP antibody, si:dkey-186m8.3 antibody, cenp-h antibody, centromere protein H antibody, centromere protein H pseudogene antibody, CENPH antibody, Cenph antibody, cenph antibody, LOC100356112 antibody, LOC101788801 antibody

Background: Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.Synonyms: CENPH, Centromere protein H, ICEN35, Interphase centromere complex protein 35

Molecular Weight: 28481 Da

Gene ID: 64946

NCBI Accession: NP_075060