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L1CAM antibody (C-Term)
L1CAM
Reactivity: Human, Mouse
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-L1CAM Antibody
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Target
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L1CAM
(L1 Cell Adhesion Molecule (L1CAM))
Binding Specificity
All epitopes for L1CAM antibodies
AA 1153-1182, C-Term
Reactivity
All reactivities for L1CAM antibodies
Human, Mouse
Host
All hosts for L1CAM antibodies
Rabbit
Clonality
All clonalities for L1CAM antibodies
Polyclonal
Conjugate
All conjugates for L1CAM antibodies
This L1CAM antibody is un-conjugated
Application
All applications for L1CAM antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects CD171 / L1CAM at C-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human, Mouse
Purification
Purified through a protein A column, followed by peptide affinity purification.
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 1153-1182aa) of human CD171 / L1CAM.
Isotype
Ig Fraction
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Discover our top product L1CAM Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for L1CAM
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Target
L1CAM
(L1 Cell Adhesion Molecule (L1CAM))
Alternative Name
CD171 / L1CAM (L1CAM Products )
Synonyms
l1cam-a antibody, CAML1 antibody, CD171 antibody, HSAS antibody, HSAS1 antibody, MASA antibody, MIC5 antibody, N-CAM-L1 antibody, N-CAML1 antibody, NCAM-L1 antibody, S10 antibody, SPG1 antibody, L1 antibody, Hsas antibody, Hyd antibody, NCAML1 antibody, L1 cell adhesion molecule S homeolog antibody, L1 cell adhesion molecule antibody, l1cam.S antibody, L1CAM antibody, L1cam antibody
Background
L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.Synonyms: CAML1, MIC5, N-CAM L1, Neural cell adhesion molecule L1
Gene ID
3897
NCBI Accession
NP_000416
Pathways
Synaptic Membrane
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