CBY1/PGEA1 antibody (C-Term)

Catalog No. ABIN951076

Product Details anti-CBY1/PGEA1 Antibody

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Binding Specificity: AA 97-126, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBY1/PGEA1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human CBY1 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 97~126 amino acids from the C-terminal region of human CBY1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CBY1/PGEA1

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Alternative Name: CBY1 (CBY1 Products)

Synonyms: chibby antibody, cby antibody, arb1 antibody, pgea1 antibody, pigea14 antibody, pigea-14 antibody, hs508i15a antibody, C22orf2 antibody, CBY antibody, HS508I15A antibody, PGEA1 antibody, PIGEA-14 antibody, PIGEA14 antibody, 1110014P06Rik antibody, PGEA14 antibody, Pgea1 antibody, chibby homolog 1 S homeolog antibody, chibby homolog 1 antibody, chibby family member 1, beta catenin antagonist antibody, cby1.S antibody, cby1 antibody, CBY1 antibody, Cby1 antibody

Background: Inhibits the Wnt/Wingless pathway by binding to beta catenin and inhibiting beta catenin mediated transcriptional activation by competing with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin 2/PKD2 and possibly of other intracellular proteins.Synonyms: ARB1, ARPP-binding protein, C22orf2, CBY, Cytosolic leucine-rich protein, Golgi and endoplasmic reticulum-associated 1, HRIHFB2025, PGEA1, PIGEA-14, PKD2 interactor, Protein chibby homolog 1

Molecular Weight: 14470 Da

Gene ID: 25776

NCBI Accession: NP_001002880