CASC4 antibody (C-Term)

Catalog No. ABIN951049

Product Details anti-CASC4 Antibody

Target: CASC4 (Cancer Susceptibility Candidate 4 (CASC4))

Binding Specificity: AA 343-373, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASC4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CASC4.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 343-373 amino acids from the C-terminal region of human CASC4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CASC4

Target: CASC4 (Cancer Susceptibility Candidate 4 (CASC4))

Alternative Name: CASC4 (CASC4 Products)

Synonyms: H63 antibody, D130060C09Rik antibody, VGFG2573 antibody, cancer susceptibility 4 antibody, cancer susceptibility candidate 4 antibody, cancer susceptibility 4 L homeolog antibody, CASC4 antibody, Casc4 antibody, casc4.L antibody

Background: The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30 % of human breast and 20 % of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.Synonyms: Cancer susceptibility candidate gene 4 protein

Molecular Weight: 48864 Da

Gene ID: 113201

NCBI Accession: NP_612432