GDF5 antibody (C-Term)

Catalog No. ABIN950667

Product Details anti-GDF5 Antibody

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Binding Specificity: AA 350-379, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human BMP14 / GDF5 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: conjugated synthetic peptide between 350-379 amino acids from the C-terminal region of human BMP14 / GDF5

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GDF5

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Alternative Name: BMP14 / GDF5 (GDF5 Products)

Synonyms: CDMP1 antibody, gdf antibody, gdf-5 antibody, GDF5 antibody, BDA1C antibody, BMP14 antibody, LAP4 antibody, OS5 antibody, SYM1B antibody, SYNS2 antibody, Cdmp-1 antibody, bp antibody, brp antibody, Cdmp1 antibody, growth differentiation factor 5 L homeolog antibody, growth differentiation factor 5 antibody, gdf5.L antibody, GDF5 antibody, Gdf5 antibody

Background: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.Synonyms: Bone Morphogenetic Protein 14, CDMP1, Cartilage-derived morphogenetic protein 1, GDF-5, Growth/differentiation factor 5, Radotermin

Molecular Weight: 55411 Da

Gene ID: 8200

NCBI Accession: NP_000548