Azurocidin antibody (Middle Region)

Catalog No. ABIN950583

Product Details anti-Azurocidin Antibody

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Binding Specificity: AA 66-96, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Azurocidin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Azurocidin.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 66-96 amino acids from the Central region of human AZU1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Azurocidin

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Alternative Name: Azurocidin (AZU1 Products)

Synonyms: AZAMP antibody, AZU antibody, CAP37 antibody, HBP antibody, HUMAZUR antibody, NAZC antibody, AZU1 antibody, Azurocidin antibody, pHBP antibody, azurocidin 1 antibody, azurocidin antibody, AZU1 antibody, CpipJ_CPIJ007384 antibody

Background: Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.Synonyms: CAP37, Cationic antimicrobial protein CAP37, HBP, Heparin-binding protein

Gene ID: 566

NCBI Accession: NP_001691