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NAE1 antibody (Middle Region)
NAE1
Reactivity: Human
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NAE1 Antibody
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Target
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NAE1
(NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
Binding Specificity
All epitopes for NAE1 antibodies
AA 171-200, Middle Region
Reactivity
All reactivities for NAE1 antibodies
Human
Host
All hosts for NAE1 antibodies
Rabbit
Clonality
All clonalities for NAE1 antibodies
Polyclonal
Conjugate
All conjugates for NAE1 antibodies
This NAE1 antibody is un-conjugated
Application
All applications for NAE1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human APPBP1 (Center).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 171-200 amino acids from the Central region of human APPBP1 Genename: NAE1
Isotype
Ig Fraction
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Discover our top product NAE1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for NAE1
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Target
NAE1
(NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
Alternative Name
APPBP1 (NAE1 Products )
Synonyms
APPBP1 antibody, CG7828 antibody, Dmel\\CG7828 antibody, anon-WO0140519.225 antibody, dAPP-BP1 antibody, dAPPBP1 antibody, A-116A10.1 antibody, ula-1 antibody, Appbp1 antibody, 59kDa antibody, appbp1 antibody, zgc:66148 antibody, beta-Amyloid precursor protein binding protein 1 antibody, NEDD8 activating enzyme E1 subunit 1 antibody, NEDD8 activating enzyme E1 subunit 1 S homeolog antibody, nedd8 activating enzyme E1 subunit 1 antibody, NEDD8-activating enzyme E1 regulatory subunit antibody, APP-BP1 antibody, NAE1 antibody, Nae1 antibody, nae1.S antibody, nae1 antibody, ula-1 antibody
Background
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.Synonyms: Amyloid beta precursor protein-binding protein 1, Amyloid protein-binding protein 1, HPP1, NAE1
Molecular Weight
60246 Da
Gene ID
8883
NCBI Accession
NP_001018169
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