CHIA antibody (N-Term)

Catalog No. ABIN950393

Product Details anti-CHIA Antibody

Target: CHIA (Chitinase, Acidic (CHIA))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHIA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CHIA.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human CHIA

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CHIA

Target: CHIA (Chitinase, Acidic (CHIA))

Alternative Name: AMCase (CHIA Products)

Synonyms: chia-a antibody, AMCASE antibody, CHIT2 antibody, TSA1902 antibody, 2200003E03Rik antibody, AMCase antibody, YNL antibody, CHIA antibody, chioIIa antibody, fa55g10 antibody, wu:fa55g10 antibody, zgc:63792 antibody, acidic mammalian chitinase antibody, chitinase, acidic antibody, chitinase, acidic S homeolog antibody, chitinase-M31, acidic antibody, chitinase, acidic 1 antibody, chitinase, acidic.4 antibody, LOC703284 antibody, CHIA antibody, LOC100600050 antibody, chia.S antibody, CHIA-M31 antibody, Chia1 antibody, Chia antibody, chia.4 antibody

Background: CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.Synonyms: Acidic mammalian chitinase, CHIA, Lung-specific protein TSA1902, TSA1902

Molecular Weight: 52271 Da

Gene ID: 27159

NCBI Accession: NP_068569