AGLU antibody (N-Term)

Catalog No. ABIN950380

Product Details anti-AGLU Antibody

Target: AGLU (alpha-Glucosidase (AGLU))

Binding Specificity: AA 173-203, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGLU antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes Human Alpha-glucosidase (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: conjugated synthetic peptide between 173-203 amino acids from the N-terminal region of Human Alpha-glucosidase Genename: GAA

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AGLU

Target: AGLU (alpha-Glucosidase (AGLU))

Alternative Name: alpha-Glucosidase (AGLU Products)

Synonyms: MG antibody, MGA antibody, SPAC56F8.01 antibody, SPAC922.02c antibody, CG11909 antibody, CT33098 antibody, Dmel\\CG11909 antibody, GB19017 antibody, 6030407P20Rik antibody, maltase-glucoamylase antibody, alpha-glucosidase (predicted) antibody, alpha-glucosidase antibody, glucosidase, alpha, acid antibody, target of brain insulin antibody, sucrase-isomaltase antibody, MGAM antibody, SPAC30D11.01c antibody, LMOf2365_0194 antibody, SPAC1039.11c antibody, Gaa antibody, tobi antibody, SI antibody, Hbg3 antibody, Mgam antibody

Background: This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene.Synonyms: Acid maltase, Aglucosidase alfa, GAA, LYAG, Lysosomal alpha-glucosidase

Molecular Weight: 105319 Da

Gene ID: 2548

NCBI Accession: NP_000143

Pathways: Cellular Glucan Metabolic Process