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ALOXE3 antibody (Middle Region)
ALOXE3
Reactivity: Human, Mouse
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ALOXE3 Antibody
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Target
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ALOXE3
(Arachidonate Lipoxygenase 3 (ALOXE3))
Binding Specificity
All epitopes for ALOXE3 antibodies
AA 230-260, Middle Region
Reactivity
Human, Mouse
Host
All hosts for ALOXE3 antibodies
Rabbit
Clonality
All clonalities for ALOXE3 antibodies
Polyclonal
Conjugate
All conjugates for ALOXE3 antibodies
This ALOXE3 antibody is un-conjugated
Application
All applications for ALOXE3 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to ALOXE3.
Cross-Reactivity (Details)
Species reactivity (tested):Human and Mouse.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 230-260 amino acids from the Central region of human ALOXE3
Isotype
Ig Fraction
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Discover our top product ALOXE3 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for ALOXE3
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Target
ALOXE3
(Arachidonate Lipoxygenase 3 (ALOXE3))
Alternative Name
ALOXE3 (ALOXE3 Products )
Synonyms
e-lox antibody, elox3 antibody, ARCI3 antibody, E-LOX antibody, eLOX3 antibody, e-LOX-3 antibody, ALOX15B antibody, arachidonate lipoxygenase 3 antibody, arachidonate lipoxygenase 3 L homeolog antibody, arachidonate 15-lipoxygenase, type B antibody, ALOXE3 antibody, aloxe3.L antibody, aloxe3 antibody, Aloxe3 antibody, ALOX15B antibody
Background
ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.Synonyms: Epidermis-type lipoxygenase 3, e-LOX-3, eLOX3
Gene ID
59344
NCBI Accession
NP_001159432
Pathways
Cell-Cell Junction Organization
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