AEBP1 antibody (Middle Region)

Catalog No. ABIN950289

Product Details anti-AEBP1 Antibody

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Binding Specificity: AA 341-372, Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AEBP1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to AEBP1.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 341-372 amino acids from the Central region of human AEBP1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AEBP1

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Alternative Name: AEBP1 / ACLP (AEBP1 Products)

Synonyms: ACLP antibody, AE binding protein 1 antibody, Closa_4071 antibody, AEBP1 antibody, Aebp1 antibody

Background: The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. Adipocyte-enhancer binding protein 1 may play a role in differentiated vascular smooth muscle cells.Synonyms: AE-binding protein 1, Adipocyte enhancer-binding protein 1, Aortic carboxypeptidase-like protein

Gene ID: 165

NCBI Accession: NP_001120