Acrosin antibody (C-Term)

Catalog No. ABIN950252

Product Details anti-Acrosin Antibody

Target: Acrosin (ACR)

Binding Specificity: AA 392-421, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acrosin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Acrosin (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 392~421 amino acids from the C-terminal region of Human ACR Genename: ACR

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Acrosin

Target: Acrosin (ACR)

Alternative Name: Acrosin / ACR (ACR Products)

Synonyms: ACR antibody, MGC130972 antibody, Acro antibody, Acrosin antibody, acrosin antibody, acrosin L homeolog antibody, acrosin prepropeptide antibody, ACR antibody, acr.L antibody, Acr antibody

Background: ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.Synonyms: 53 kDa fucose-binding protein

Gene ID: 49

NCBI Accession: NP_001088

Pathways: cAMP Metabolic Process