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AIM2 antibody (AA 1-343)

AIM2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN948806
  • Target See all AIM2 Antibodies
    AIM2 (Absent in Melanoma 2 (AIM2))
    Binding Specificity
    • 16
    • 11
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-343
    Reactivity
    • 72
    • 25
    • 19
    • 3
    • 3
    • 1
    Human
    Host
    • 60
    • 11
    • 2
    Rabbit
    Clonality
    • 65
    • 8
    Polyclonal
    Conjugate
    • 36
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIM2 antibody is un-conjugated
    Application
    • 62
    • 33
    • 32
    • 22
    • 13
    • 13
    • 12
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Purpose
    Rabbit polyclonal antibody raised against a full-length human AIM2 protein.
    Sequence
    MESKYKEILL LTGLDNITDE ELDRFKFFLS DEFNIATGKL HTANRIQVAT LMIQNAGAVS AVMKTIRIFQ KLNYMLLAKR LQEEKEKVDK QYKSVTKPKP LSQAEMSPAA SAAIRNDVAK QRAAPKVSPH VKPEQKQMVA QQESIREGFQ KRCLPVMVLK AKKPFTFETQ EGKQEMFHAT VATEKEFFFV KVFNTLLKDK FIPKRIIIIA RYYRHSGFLE VNSASRVLDA ESDQKVNVPL NIIRKAGETP KINTLQTQPL GTIVNGLFVV QKVTEKKKNI LFDLSDNTGK MEVLGVRNED TMKCKEGDKV RLTFFTLSKN GEKLQLTSGV HSTIKVIKAK KKT
    Cross-Reactivity
    Human
    Characteristics
    Antibody reactive against mammalian transfected lysate.
    Immunogen
    AIM2 (NP_004824.1, 1 a.a. ~ 343 a.a) full-length human protein.
    Top Product
    Discover our top product AIM2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    No additive
    Preservative
    Without preservative
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Adamczak, de Rivero Vaccari, Dale, Brand, Nonner, Bullock, Dahl, Dietrich, Keane: "Pyroptotic neuronal cell death mediated by the AIM2 inflammasome." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 34, Issue 4, pp. 621-9, (2014) (PubMed).

  • Target
    AIM2 (Absent in Melanoma 2 (AIM2))
    Alternative Name
    AIM2 (AIM2 Products)
    Synonyms
    AIM2 antibody, PYHIN4 antibody, Gm1313 antibody, Ifi210 antibody, absent in melanoma 2 antibody, AIM2 antibody, Aim2 antibody
    Background
    Full Gene Name: absent in melanoma 2
    Synonyms: PYHIN4
    Gene ID
    9447
    NCBI Accession
    NM_004833
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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