SGPL1 antibody (AA 1-568)

Catalog No. ABIN948744

Product Details anti-SGPL1 Antibody

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Binding Specificity: AA 1-568

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against a full-length human SGPL1 protein.

Sequence: MPSTDLLMLK AFEPYLEILE VYSTKAKNYV NGHCTKYEPW QLIAWSVVWT LLIVWGYEFV FQPESLWSRF KKKCFKLTRK MPIIGRKIQD KLNKTKDDIS KNMSFLKVDK EYVKALPSQG LSSSAVLEKL KEYSSMDAFW QEGRASGTVY SGEEKLTELL VKAYGDFAWS NPLHPDIFPG LRKIEAEIVR IACSLFNGGP DSCGCVTSGG TESILMACKA YRDLAFEKGI KTPEIVAPQS AHAAFNKAAS YFGMKIVRVP LTKMMEVDVR AMRRAISRNT AMLVCSTPQF PHGVIDPVPE VAKLAVKYKI PLHVDACLGG FLIVFMEKAG YPLEHPFDFR VKGVTSISAD THKYGYAPKG SSLVLYSDKK YRNYQFFVDT DWQGGIYASP TIAGSRPGGI SAACWAALMH FGENGYVEAT KQIIKTARFL KSELENIKGI FVFGNPQLSV IALGSRDFDI YRLSNLMTAK GWNLNQLQFP PSIHFCITLL HARKRVAIQF LKDIRESVTQ IMKNPKAKTT GMGAIYGMAQ TTVDRNMVAE LSSVFLDSLY STDTVTQGSQ MNGSPKPH

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: SGPL1 (NP_003892.2, 1 a.a. ~ 568 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SGPL1 antibody (ABIN948744)

Engel, Adamus, Frank, Kraft, Kühn, Müller, Nebe, Kasten, Seitz: "First evidence of SGPL1 expression in the cell membrane silencing the extracellular S1P siren in mammary epithelial cells." in: PLoS ONE, Vol. 13, Issue 5, pp. e0196854, (2018) (PubMed).

Target Details for SGPL1

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Alternative Name: SGPL1 (SGPL1 Products)

Synonyms: SGPL1 antibody, zgc:162153 antibody, AI428538 antibody, D10Xrf456 antibody, S1PL antibody, Spl antibody, SPL antibody, Spgl1 antibody, spl antibody, sphingosine-1-phosphate lyase 1 antibody, sphingosine-1-phosphate lyase 1 L homeolog antibody, sphingosine phosphate lyase 1 antibody, SGPL1 antibody, sgpl1.L antibody, sgpl1 antibody, Sgpl1 antibody

Background: Full Gene Name: sphingosine-1-phosphate lyase 1
Synonyms: FLJ13811,KIAA1252,SPL

Gene ID: 8879

NCBI Accession: NM_003901

Pathways: Platelet-derived growth Factor Receptor Signaling