MLL2 antibody (AA 1487-1586)

Catalog No. ABIN948660

Product Details anti-MLL2 Antibody

Target: MLL2 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Binding Specificity: AA 1487-1586

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MLL2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Mouse monoclonal antibody raised against a partial recombinant MLL2.

Sequence: SKLEGMFPAY LQEAFFGKEL LDLSRKALFA VGVGRPSFGL GTPKAKGDGG SERKELPTSQ KGDDGPDIAD EESRGLEGKA DTPGPEDGGV KASPVPSDPE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MLL2 (NP_003473.1, 1487 a.a. ~ 1586 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2E1

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MLL2 antibody (ABIN948660)

Micale, Augello, Maffeo, Selicorni, Zucchetti, Fusco, De Nittis, Pellico, Mandriani, Fischetto, Boccone, Silengo, Biamino, Perria, Sotgiu, Serra, Lapi, Neri, Ferlini, Cavaliere, Chiurazzi, Monica et al.: "Molecular analysis, pathogenic mechanisms, and readthrough therapy on a large cohort of Kabuki syndrome patients. ..." in: Human mutation, Vol. 35, Issue 7, pp. 841-50, (2014) (PubMed).

Target Details for MLL2

Target: MLL2 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Alternative Name: MLL2 (MLL2 Products)

Synonyms: AAD10 antibody, ALR antibody, CAGL114 antibody, KABUK1 antibody, KMS antibody, MLL2 antibody, MLL4 antibody, TNRC21 antibody, HRX2 antibody, MLL1B antibody, TRX2 antibody, WBP7 antibody, BC032281 antibody, BC058659 antibody, C430014K11Rik antibody, KMT2B antibody, Mll2 antibody, Mll4 antibody, lysine methyltransferase 2D antibody, lysine methyltransferase 2B antibody, lysine (K)-specific methyltransferase 2D antibody, myeloid/lymphoid or mixed-lineage leukemia 2 antibody, KMT2D antibody, KMT2B antibody, Kmt2d antibody, MLL2 antibody

Background: Full Gene Name: myeloid/lymphoid or mixed-lineage leukemia 2
Synonyms: AAD10,ALR,CAGL114,MLL4,TNRC21

Gene ID: 8085

NCBI Accession: NM_003482

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effect