C-Peptide antibody
(2 references)-
- Target See all C-Peptide Antibodies
- C-Peptide
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This C-Peptide antibody is un-conjugated
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Application
- ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)
- Specificity
- The mouse monoclonal antibody C-PEP-01 reacts specifically with C-peptide, a part of the proinsulin molecule. Proinsulin consists of three parts: C-peptide and two long strands of amino acids (alpha and beta chains, later become linked together to form the insulin molecule). No cross-reactivity with insulin or other peptide hormones or proteins was observed.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Immunogen
- Human C-peptide conjugated to bovine serum albumin.
- Clone
- C-PEP-01
- Isotype
- IgG1
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anti-C-Peptide antibody (Biotin)
Reactivity: Human ELISA, ICC, IHC (p), RIA Host: Mouse Monoclonal C-PEP-01 Biotin
anti-C-Peptide antibodyReactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-C-Peptide antibodyReactivity: Rat WB, IHC, IP, ICC Host: Mouse Monoclonal C5 unconjugated
anti-C-Peptide antibodyReactivity: Human, Rat WB Host: Goat Polyclonal unconjugated
anti-C-Peptide antibodyReactivity: Human WB, IHC Host: Mouse Monoclonal unconjugated
anti-C-Peptide antibodyReactivity: Human IHC (fro), EIA Host: Mouse Monoclonal HCP-B2 unconjugated
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- Application Notes
- Immunohistochemistry (paraffin sections): Recommended dilution: 2-5 μg/mL, positive control: human pancreas (islets of Langerhans).
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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-
: "An acidic pH and activation of phosphoinositide 3-kinase stimulate differentiation of pancreatic progenitors into insulin-producing cells." in: Transplantation proceedings, Vol. 42, Issue 6, pp. 2075-80, (2010) (PubMed).
: "A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA." in: Hybridoma, Vol. 10, Issue 3, pp. 379-86, (1991) (PubMed).
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: "An acidic pH and activation of phosphoinositide 3-kinase stimulate differentiation of pancreatic progenitors into insulin-producing cells." in: Transplantation proceedings, Vol. 42, Issue 6, pp. 2075-80, (2010) (PubMed).
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- Target
- C-Peptide
- Abstract
- C-Peptide Products
- Synonyms
- insulin 2 antibody, Ins2 antibody
- Background
- From every molecule of proinsulin, one molecule of insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to insulin.,C-peptide of proinsulin
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