CD72 antibody
(1 reference)-
- Target See all CD72 Antibodies
- CD72 (CD72 Molecule (CD72))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD72 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificity
- The mouse monoclonal antibody 3F3 recognizes an extracellular epitope of CD72, a 39-43 kDa type II membrane glycoprotein (C-type lectin family). CD72 is a pan-B cell marker expressed throughout the B lymphocytes diferentiation with the exception of plasma cells, it is also present on follicular dendritic cells.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Immunogen
- Normal human lymphocytes from a lymph node.
- Clone
- 3F3
- Isotype
- IgG2b
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anti-CD72 Molecule (CD72) (AA 117-359) antibody
CD72 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 2F3B8 unconjugated
anti-CD72 Molecule (CD72) (AA 117-359) antibodyCD72 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 4G4B1 unconjugated
anti-CD72 Molecule (CD72) (AA 169-359) antibodyCD72 Reactivity: Human WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-CD72 Molecule (CD72) (AA 143-345) antibodyCD72 Reactivity: Mouse WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-CD72 Molecule (CD72) (AA 126-237) antibodyCD72 Reactivity: Rat WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-CD72 Molecule (CD72) antibodyCD72 Reactivity: Human FACS, ELISA, IHC, IF, Coat, StM Host: Mouse Monoclonal BU40 unconjugated
anti-CD72 Molecule (CD72) (AA 150-208) antibodyCD72 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-CD72 Molecule (CD72) (AA 4-110) antibodyCD72 Reactivity: Human FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-CD72 Molecule (CD72) antibody (PE)CD72 Reactivity: Human FACS Host: Mouse Monoclonal 3F3 PE
anti-CD72 Molecule (CD72) (AA 117-226) antibodyCD72 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4D10 unconjugated
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- Application Notes
- Flow cytometry: Recommended dilution: 1 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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-
: "CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72." in: PLoS ONE, Vol. 2, Issue 9, pp. e818, (2007) (PubMed).
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: "CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72." in: PLoS ONE, Vol. 2, Issue 9, pp. e818, (2007) (PubMed).
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- Target
- CD72 (CD72 Molecule (CD72))
- Alternative Name
- CD72 (CD72 Products)
- Synonyms
- CD72c antibody, Ly-19 antibody, Ly-32 antibody, Ly-m19 antibody, Lyb-2 antibody, CD72b antibody, LYB2 antibody, CD72 antigen antibody, CD72 molecule antibody, Cd72 antibody, CD72 antibody
- Background
- CD72 Molecule,CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.,LYB2
- Gene ID
- 971
- UniProt
- P21854
- Pathways
- BCR Signaling
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