CD7 antibody
(1 reference)-
- Target See all CD7 Antibodies
- CD7
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD7 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- The antibody MEM-186 reacts with an extracellular epitope of CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Immunogen
- Human acute myelogenous leukaemia cell line KG-1.
- Clone
- MEM-186
- Isotype
- IgG1
- Top Product
- Discover our top product CD7 Primary Antibody
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anti-CD7 (CD7) (AA 26-134) antibody
CD7 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD7 (CD7) (AA 23-128) antibodyCD7 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 Reactivity: Human FACS, ELISA, IHC Host: Mouse Monoclonal 3D11F12 unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 2B1C9 unconjugated
anti-CD7 (CD7) (AA 72-175) antibodyCD7 Reactivity: Human FACS, ELISA, IHC Host: Mouse Monoclonal 5B10E3 unconjugated
anti-CD7 (CD7) antibodyCD7 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-CD7 (CD7) (AA 24-150) antibodyCD7 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD7 (CD7) (AA 21-240) antibodyCD7 Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 1B8 unconjugated
anti-CD7 (CD7) antibodyCD7 Reactivity: Human IHC Host: Rabbit Monoclonal MSVA-007R unconjugated Recombinant Antibody
anti-CD7 (CD7) antibodyGMP Grade CD7 Reactivity: Human FACS Host: Mouse Monoclonal 4H9 unconjugated
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- Application Notes
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Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL, positive tissue: spleen.
Flow cytometry: Recommended dilution: 2 μg/mL.
Western blotting: Non-reducing conditions. - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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-
: "The CD3-zeta chimeric antigen receptor overcomes TCR Hypo-responsiveness of human terminal late-stage T cells." in: PLoS ONE, Vol. 7, Issue 1, pp. e30713, (2012) (PubMed).
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: "The CD3-zeta chimeric antigen receptor overcomes TCR Hypo-responsiveness of human terminal late-stage T cells." in: PLoS ONE, Vol. 7, Issue 1, pp. e30713, (2012) (PubMed).
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- Target
- CD7
- Alternative Name
- CD7 (CD7 Products)
- Synonyms
- GP40 antibody, LEU-9 antibody, TP41 antibody, Tp40 antibody, CD7 molecule antibody, CD7 antigen antibody, Cd7 molecule antibody, CD7 antibody, Cd7 antibody
- Background
- CD7 Molecule,CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.,GP40, TLA, TP41, LEU-9
- Gene ID
- 924
- UniProt
- P09564
- Pathways
- Cell-Cell Junction Organization
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