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L-Selectin antibody

SELL Reactivity: Human, Cow FACS, IP, ICC Host: Mouse Monoclonal IVA94 unconjugated
Catalog No. ABIN94209
  • Target See all L-Selectin (SELL) Antibodies
    L-Selectin (SELL) (Selectin L (SELL))
    Reactivity
    • 104
    • 70
    • 34
    • 17
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Cow
    Host
    • 80
    • 61
    • 50
    • 1
    Mouse
    Clonality
    • 138
    • 49
    • 3
    Monoclonal
    Conjugate
    • 69
    • 28
    • 22
    • 16
    • 13
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This L-Selectin antibody is un-conjugated
    Application
    • 142
    • 60
    • 51
    • 44
    • 33
    • 20
    • 17
    • 10
    • 10
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificity
    The antibody IVA94 reacts with an extracellular epitope of CD62L antigen (bovine). CD62L (L-selectin) is a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes, it is also present on a subset of NK cells and certain hematopoietic malignant cells.
    Cross-Reactivity (Details)
    Bovine
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Bovine leukocytes.
    Clone
    IVA94
    Isotype
    IgG1
    Top Product
    Discover our top product SELL Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Howard: "Ruminant cluster CD62L." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 255-6, (1997) (PubMed).

    Naessens, Nthale, Muiya: "Biochemical analysis of preliminary clusters in the non-lineage panel." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 347-56, (1997) (PubMed).

    Naessens, Howard, Hopkins: "Nomenclature and characterization of leukocyte differentiation antigens in ruminants." in: Immunology today, Vol. 18, Issue 8, pp. 365-8, (1997) (PubMed).

  • Target
    L-Selectin (SELL) (Selectin L (SELL))
    Alternative Name
    CD62L (SELL Products)
    Synonyms
    CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody, LSEL antibody, LYAM1 antibody, PLNHR antibody, TQ1 antibody, A.11 antibody, L-selectin antibody, LECAM-1 antibody, SELE antibody, AI528707 antibody, Lnhr antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, Lyam1 antibody, selectin L antibody, selectin, lymphocyte antibody, SELL antibody, Sell antibody
    Background
    Selectin L,CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).,L-selectin, LSEL, SELL, LAM1, LECAM1, LEU8, LNHR, LYAM1, PLNHR
    Gene ID
    281485
    UniProt
    P98131
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