Integrin Alpha2b antibody
(1 reference)-
- Target See all Integrin Alpha2b (CD41) Antibodies
- Integrin Alpha2b (CD41)
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Reactivity
- Human, Non-Human Primate
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Integrin Alpha2b antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- The antibody HIP2 reacts with an extracellular epitope on beta (b) subunit of CD41 glycoprotein (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
- Cross-Reactivity (Details)
- Human, Non-Human Primates
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Clone
- HIP2
- Isotype
- IgG3
- Top Product
- Discover our top product CD41 Primary Antibody
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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 Reactivity: Human FACS, ELISA, IHC Host: Mouse Monoclonal 2E10C9 unconjugated
anti-Integrin Alpha2b (CD41) (AA 351-450) antibodyCD41 Reactivity: Human, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p), Func Host: Rat Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p) Host: Rat Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 639-887) antibodyCD41 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated
anti-Integrin Alpha2b (CD41) antibody (PE)CD41 Reactivity: Mouse FACS Host: Rat Monoclonal MWReg30 PE
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- Application Notes
- Flow cytometry: Recommended dilution: 1-4 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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: "[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." in: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).
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: "[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." in: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).
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- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- CD41b (CD41 Products)
- Synonyms
- AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
- Background
- Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,GT, GTA, GP2B, HPA3, GPIIb
- Gene ID
- 3674
- UniProt
- P08514
- Pathways
- Integrin Complex
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