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beta Endorphin antibody
beta-EP
Reactivity: Human
IHC (fro), IHC (p)
Host: Mouse
Monoclonal
B31-15
unconjugated
Product Details anti-beta Endorphin Antibody
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Target
See all beta Endorphin (beta-EP) Antibodies
beta Endorphin (beta-EP)
(Endorphin beta (beta-EP))
Reactivity
All reactivities for beta Endorphin antibodies
Human
Host
All hosts for beta Endorphin antibodies
Mouse
Clonality
All clonalities for beta Endorphin antibodies
Monoclonal
Conjugate
All conjugates for beta Endorphin antibodies
This beta Endorphin antibody is un-conjugated
Application
All applications for beta Endorphin antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
The mouse monoclonal antibody B31.15 reacts with human beta Endorphin, an endogenous opiate derived from ACTH gene. ACTH (Corticotropin, human 39 aa) is synthesized by the anterior pituitary gland and stimulates the adrenal cortex, 6 hormones are derived from one ACTH gene: ACTH, lipotropin, alpha-MSH, beta-MSH, endorphin, and one other.
Cross-Reactivity (Details)
Other not tested, Human
Purification
Purified by protein-A affinity chromatography.
Purity
> 95 % (by SDS-PAGE)
Immunogen
Human beta Endorphin (full length native protein).
Clone
B31-15
Isotype
IgG1
Alternatives
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Application Details
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Application Notes
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, standard ABC technique (DAB+), heat retrieval (microwave oven), incubation: overnight at 4 °C, positive tissue: human pituitary gland.
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Do not freeze.
Storage
4 °C
Storage Comment
Store at 2-8°C. Do not freeze.
References for anti-beta Endorphin antibody (ABIN93907)
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Andjelkov, Elvenes, Figenschau, Bjorkoy, Knutsen, Seternes, Johansen : "Detection of mRNA transcripts of truncated opiate precursor (POMC) in human cartilage. " in: Cell biochemistry and function , Vol. 24 , Issue 3 , pp. 229-35 , (2006 ) (PubMed ).
Target Details for beta Endorphin
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Target
beta Endorphin (beta-EP)
(Endorphin beta (beta-EP))
Alternative Name
beta Endorphin (beta-EP Products )
Synonyms
ACTH antibody, BE antibody, Beta-LPH antibody, Clip antibody, Gamma-LPH antibody, Npp antibody, Pomc-1 antibody, Pomc1 antibody, alpha-MSH antibody, alphaMSH antibody, beta-MSH antibody, gamma-MSH antibody, CLIP antibody, LPH antibody, MSH antibody, NPP antibody, POC antibody, pro-opiomelanocortin-alpha antibody, proopiomelanocortin antibody, Pomc antibody, POMC antibody
Pathways
Metabolism of Steroid Hormones and Vitamin D , Peptide Hormone Metabolism , Hormone Activity
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