CD19 antibody
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- Target See all CD19 Antibodies
- CD19 (CD19 Molecule (CD19))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD19 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Purification
- Protein A affinity chromatography
- Immunogen
- CD19 antibody (Azide free) was raised in rat using murine CD19-expressing K562 human erythroleukemia cells as the immunogen.
- Clone
- 6D5
- Isotype
- IgG2a
- Top Product
- Discover our top product CD19 Primary Antibody
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- Application Notes
- Optimal conditions should be determined byt he investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Supplied as a liquid in PBS.
- Preservative
- Without preservative
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 °C.
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- Target
- CD19 (CD19 Molecule (CD19))
- Alternative Name
- CD19 (CD19 Products)
- Background
- B-lymphocyte antigen CD19 also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is encoded by the CD19 gene. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. . Synonyms: Monoclonal CD19 antibody, Anti-CD19 antibody.
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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