BMP7 antibody

Catalog No. ABIN933774

Product Details anti-BMP7 Antibody

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BMP7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Protein A affinity chromatography

Immunogen: BMP7 antibody was raised in mouse using recombinant human BMP-7/OP-1 as the immunogen.

Clone: M912263

Isotype: IgG1 kappa

Application Details

Application Notes: ELISA: 2-4 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for BMP7

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Alternative Name: BMP7 (BMP7 Products)

Synonyms: bmp-7 antibody, bmp7 antibody, op-1 antibody, BMP7 antibody, zgc:153025 antibody, OP-1 antibody, OP1 antibody, BMP-7 antibody, fb83f09 antibody, wu:fb83f09 antibody, bone morphogenetic protein 7 antibody, bone morphogenetic protein 7, gene 1 L homeolog antibody, bone morphogenetic protein 7b antibody, bone morphogenetic protein 7, gene 2 L homeolog antibody, bone morphogenetic protein 7a antibody, BMP7 antibody, bmp7.1.L antibody, LOC100136282 antibody, bmp7b antibody, Bmp7 antibody, LOC100008826 antibody, bmp7.2.L antibody, bmp7a antibody

Background: TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures. Synonyms: Monoclonal BMP7 antibody, Anti-BMP7 antibody, BMP-7 antibody, Bone Morphogenetic antibody, 7 antibody,OP-1 antibody.

Molecular Weight: 28.8 kDa (predicted detection band MW)

Pathways: Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance