Reticulon 3 antibody

Catalog No. ABIN932229

Product Details anti-Reticulon 3 Antibody

Target: Reticulon 3 (RTN3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Reticulon 3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Immunogen: RTN3 antibody was raised in Mouse using a purified recombinant fragment of RTN3 expressed in E. coli as the immunogen.

Clone: 1E11

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:10,000, IF: 1:200-1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for Reticulon 3

Target: Reticulon 3 (RTN3)

Alternative Name: RTN3 (RTN3 Products)

Background: RTN3 may be involved in membrane trafficking in the early secretory pathway. It is thought to inhibit BACE1 activity and amyloid precursor protein processing. It may also induce caspase-8 cascade and apoptosis. RTN3 may favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Synonyms: Monoclonal RTN3 antibody, Anti-RTN3 antibody, Reticulon 3 antibody.