Reticulon 3 antibody

Catalog No. ABIN932228

Product Details anti-Reticulon 3 Antibody

Target: Reticulon 3 (RTN3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Reticulon 3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Immunogen: RTN3 antibody was raised in Mouse using a purified recombinant fragment of RTN3 expressed in E. coli as the immunogen.

Clone: 10A8

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for Reticulon 3

Target: Reticulon 3 (RTN3)

Alternative Name: RTN3 (RTN3 Products)

Synonyms: ASYIP antibody, HAP antibody, NSPL2 antibody, NSPLII antibody, RTN3-A1 antibody, MGC56439 antibody, zgc:56439 antibody, zgc:77630 antibody, RTN3 antibody, hap antibody, asyip antibody, nspl2 antibody, xrtn3 antibody, nsplii antibody, rtn3-a1 antibody, RTN3w antibody, rtn3 antibody, XRTN3 antibody, rtn3-a antibody, rtn3-b antibody, reticulon 3 antibody, reticulon 3 L homeolog antibody, reticulon-3 antibody, reticulon 3 S homeolog antibody, RTN3 antibody, Rtn3 antibody, rtn3 antibody, rnt3 antibody, rtn3.L antibody, LOC107131155 antibody, rtn3.S antibody

Background: RTN3 may be involved in membrane trafficking in the early secretory pathway. It is thought to inhibit BACE1 activity and amyloid precursor protein processing. It may induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Synonyms: Monoclonal RTN3 antibody, Anti-RTN3 antibody, Reticulon 3 antibody.