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NCOR1 antibody (AA 1-192)
NCOR1
Reactivity: Human
ELISA, IHC, WB
Host: Mouse
Monoclonal
7A7A9
unconjugated
Product Details anti-NCOR1 Antibody
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Target
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NCOR1
(Nuclear Receptor Co-Repressor 1 (NCOR1))
Binding Specificity
All epitopes for NCOR1 antibodies
AA 1-192
Reactivity
All reactivities for NCOR1 antibodies
Human
Host
All hosts for NCOR1 antibodies
Mouse
Clonality
All clonalities for NCOR1 antibodies
Monoclonal
Conjugate
All conjugates for NCOR1 antibodies
This NCOR1 antibody is un-conjugated
Application
All applications for NCOR1 antibodies
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
Immunogen
NCOR1 antibody was raised in Mouse using a purified recombinant fragment of NCOR1(aa1-192) expressed in E. coli as the immunogen.
Clone
7A7A9
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Target Details for NCOR1
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Target
NCOR1
(Nuclear Receptor Co-Repressor 1 (NCOR1))
Alternative Name
NCOR1 (NCOR1 Products )
Synonyms
ncor antibody, zgc:56355 antibody, 5730405M06Rik antibody, A230020K14Rik antibody, N-CoR antibody, RIP13 antibody, Rxrip13 antibody, mKIAA1047 antibody, N-CoR1 antibody, TRAC1 antibody, hN-CoR antibody, nuclear receptor corepressor 1 antibody, nuclear receptor co-repressor 1 antibody, nuclear receptor corepressor 1 pseudogene antibody, nuclear receptor corepressor 1 S homeolog antibody, ncor1 antibody, NCOR1 antibody, CpipJ_CPIJ002507 antibody, LOC100343278 antibody, Ncor1 antibody, ncor1.S antibody
Background
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Synonyms: Monoclonal NCOR1 antibody, Anti-NCOR1 antibody, Nuclear receptor co-repressor 1 antibody, Nuclear receptor co-repressor 1 antibody.
Pathways
Nuclear Hormone Receptor Binding , Chromatin Binding , Regulation of Lipid Metabolism by PPARalpha , Regulation of Carbohydrate Metabolic Process
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