SECISBP2 antibody

Catalog No. ABIN931196

Product Details anti-SECISBP2 Antibody

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SECISBP2 antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: SECISBP2 antibody was raised in mouse using recombinant Human Secis Binding Protein 2 (Secisbp2)

Clone: 2957C2a

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: SECISBP2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for SECISBP2

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Alternative Name: SECISBP2 (SECISBP2 Products)

Synonyms: SBP2 antibody, 2210413N07Rik antibody, 2810012K13Rik antibody, CG7066 antibody, Dmel\\CG7066 antibody, DKFZp459F1026 antibody, Sbp2 antibody, SECIS binding protein 2 antibody, SECIS-binding protein 2 antibody, Secisbp2 antibody, Sbp2 antibody, SECISBP2 antibody, secisbp2 antibody

Background: The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteinespecific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Synonyms: Monoclonal SECISBP2 antibody, Anti-SECISBP2 antibody, SECIS binding protein 2 antibody, SBP2 antibody, DKFZp686C09169 antibody.