HEXIM1 antibody

Catalog No. ABIN931145

Product Details anti-HEXIM1 Antibody

Target: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HEXIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: HEXIM1 antibody was raised in mouse using recombinant Human Hexamethylene Bis-Acetamide Inducible 1

Clone: 2416C2a

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: HEXIM1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for HEXIM1

Target: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Alternative Name: HEXIM1 (HEXIM1 Products)

Synonyms: HEXIM1 antibody, fd44h02 antibody, hexim antibody, wu:fd44h02 antibody, zgc:162976 antibody, CLP1 antibody, EDG1 antibody, HIS1 antibody, MAQ1 antibody, 7330426E13Rik antibody, CLP-1 antibody, Clp1 antibody, Clp-1 antibody, hexamethylene bisacetamide inducible 1 antibody, hexamethylene bis-acetamide inducible 1 antibody, hexamethylene bis-acetamide inducible 1 L homeolog antibody, HEXIM1 antibody, hexim1 antibody, Hexim1 antibody, hexim1.L antibody

Background: This gene is a transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Synonyms: Monoclonal HEXIM1 antibody, Anti-HEXIM1 antibody, Hexamethylene bis- acetamide inducible 1 antibody, CLP1 antibody, EDG1 antibody, HIS1 antibody, MAQ1 antibody, FLJ13562 antibody.