Id2 antibody

Catalog No. ABIN931106

Product Details anti-Id2 Antibody

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Id2 antibody is un-conjugated

Application: Dot Blot (DB), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: ID2 antibody was raised in mouse using recombinant Human Inhibitor Of Dna Binding 2, Dominant Negative Helix-Loop-Helix Protein (Id2)

Clone: 2457C5a

Isotype: IgG1

Application Details

Application Notes: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: ID2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for Id2

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Alternative Name: ID2 (Id2 Products)

Background: The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. Synonyms: Monoclonal ID2 antibody, Anti-ID2 antibody, inhibitor of DNA binding 2 dominant negative helix-loop-helix protein antibody, GIG8 antibody, ID2A antibody, ID2H antibody, MGC26389 antibody.