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RHOB antibody

RHOB Reactivity: Human DB Host: Mouse Monoclonal 2916C2a unconjugated
Catalog No. ABIN931074
  • Target See all RHOB Antibodies
    RHOB (Ras Homolog Gene Family, Member B (RHOB))
    Reactivity
    • 45
    • 19
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 1
    • 1
    Mouse
    Clonality
    • 45
    • 1
    Monoclonal
    Conjugate
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RHOB antibody is un-conjugated
    Application
    • 19
    • 13
    • 13
    • 13
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Dot Blot (DB)
    Cross-Reactivity
    Human
    Cross-Reactivity (Details)
    Other species not studied.
    Purification
    Protein G affinity chromatography
    Immunogen
    RHOB antibody was raised in mouse using recombinant Human Ras Homolog Gene Family, Member B (Rhob)
    Clone
    2916C2a
    Isotype
    IgG1
    Top Product
    Discover our top product RHOB Primary Antibody
  • Application Notes
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    RHOB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • Target
    RHOB (Ras Homolog Gene Family, Member B (RHOB))
    Alternative Name
    RHOB (RHOB Products)
    Synonyms
    ARH6 antibody, ARHB antibody, MST081 antibody, MSTP081 antibody, RHOH6 antibody, AA017882 antibody, Arh6 antibody, Arhb antibody, RHO antibody, arha antibody, rhoa antibody, wu:fj42e08 antibody, zgc:92206 antibody, rhob antibody, xrhob antibody, ras homolog family member B antibody, ras homolog gene family, member Ab antibody, ras homolog family member B S homeolog antibody, RHOB antibody, Rhob antibody, rhoab antibody, rhob.S antibody
    Background
    RHOB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Synonyms: Monoclonal RHOB antibody, Anti-RHOB antibody, Ras homolog gene family member B antibody, ARH6 antibody, ARHB antibody, RHOH6 antibody, MST081 antibody, MSTP081 antibody.
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