MED26 antibody

Catalog No. ABIN931047

Product Details anti-MED26 Antibody

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MED26 antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: CRSP7 antibody was raised in mouse using recombinant Human Cofactor Required For Sp1 Transcriptional Activation, Subunit 7, 70 Kda (Crsp7)

Clone: 2216C1a

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: CRSP7 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for MED26

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Alternative Name: CRSP7 (MED26 Products)

Synonyms: med26 antibody, wu:fe06c07 antibody, wu:fi75a09 antibody, zgc:55993 antibody, CRSP7 antibody, CRSP70 antibody, 5730493L18Rik antibody, AI414941 antibody, AW495270 antibody, Crsp7 antibody, Slc35e1 antibody, crsp7 antibody, mediator of RNA polymerase II transcription subunit 26 antibody, cofactor required for Sp1 transcriptional activation, subunit 7 antibody, mediator complex subunit 26 antibody, mediator complex subunit 26 L homeolog antibody, LOC725023 antibody, crsp7 antibody, MED26 antibody, Med26 antibody, med26.L antibody

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Synonyms: Monoclonal CRSP7 antibody, Anti-CRSP7 antibody, Cofactor required for Sp1 transcriptional activation subunit 7 antibody, MED26 antibody, CRSP70 antibody.

Pathways: Regulation of Lipid Metabolism by PPARalpha