MED26 antibody
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- Target See all MED26 Antibodies
- MED26 (Mediator Complex Subunit 26 (MED26))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MED26 antibody is un-conjugated
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Application
- Western Blotting (WB), Dot Blot (DB)
- Cross-Reactivity
- Human
- Cross-Reactivity (Details)
- Other species not studied.
- Purification
- Protein G affinity chromatography
- Immunogen
- CRSP7 antibody was raised in mouse using recombinant Human Cofactor Required For Sp1 Transcriptional Activation, Subunit 7, 70 Kda (Crsp7)
- Clone
- 2216C1a
- Isotype
- IgG1
- Top Product
- Discover our top product MED26 Primary Antibody
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- Application Notes
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WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Buffer
- CRSP7 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- Target
- MED26 (Mediator Complex Subunit 26 (MED26))
- Alternative Name
- CRSP7 (MED26 Products)
- Background
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Synonyms: Monoclonal CRSP7 antibody, Anti-CRSP7 antibody, Cofactor required for Sp1 transcriptional activation subunit 7 antibody, MED26 antibody, CRSP70 antibody.
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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