CRNKL1 antibody

Catalog No. ABIN931026

Product Details anti-CRNKL1 Antibody

Target: CRNKL1 (Crooked Neck Pre-mRNA Splicing Factor-Like 1 (CRNKL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRNKL1 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: CRNKL1 antibody was raised in mouse using recombinant Human Crn, Crooked Neck-Like 1 (Drosophila) (Crnkl1)

Clone: 2212C1a

Isotype: IgG1

Application Details

Application Notes: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: CRNKL1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for CRNKL1

Target: CRNKL1 (Crooked Neck Pre-mRNA Splicing Factor-Like 1 (CRNKL1))

Alternative Name: CRNKL1 (CRNKL1 Products)

Background: The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. This gene is similar in sequence to crn and encodes a protein which can localize to premRNA splicing complexes in the nucleus. The encoded protein, which contains many tetratricopeptide repeats, is required for pre-mRNA splicing. Synonyms: Monoclonal CRNKL1 antibody, Anti-CRNKL1 antibody, Crooked neck pre-mRNA splicing factor-like 1 antibody, CRN antibody, HCRN antibody, MSTP021 antibody.

Pathways: Ribonucleoprotein Complex Subunit Organization