GAS41 antibody

Catalog No. ABIN930995

Product Details anti-GAS41 Antibody

Target: GAS41 (YEATS Domain Containing 4)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GAS41 antibody is un-conjugated

Application: Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: YEATS4 antibody was raised in mouse using recombinant Human Yeats Domain Containing 4 (Yeats4)

Clone: YEATB1A8

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: YEATS4 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for GAS41

Target: GAS41 (YEATS Domain Containing 4)

Alternative Name: YEATS4 (GAS41 Products)

Background: YEATS4 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Synonyms: Monoclonal YEATS4 antibody, Anti-YEATS4 antibody, YEATS domain containing 4 antibody, YAF9 antibody, GAS41 antibody,NUBI-1 antibody, 4930573H17Rik antibody, B230215M10Rik antibody.