Ubinuclein 1 antibody

Catalog No. ABIN930942

Product Details anti-Ubinuclein 1 Antibody

Target: Ubinuclein 1 (UBN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Ubinuclein 1 antibody is un-conjugated

Application: Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: UBN1 antibody was raised in mouse using recombinant Ubinuclein 1 (Ubn1)

Clone: UBN1G12

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: UBN1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for Ubinuclein 1

Target: Ubinuclein 1 (UBN1)

Alternative Name: UBN1 (UBN1 Products)

Synonyms: ubinuclein-1 antibody, ubn1 antibody, VT antibody, VT4 antibody, 1110029L11Rik antibody, 2610108L02Rik antibody, AA673476 antibody, AW124741 antibody, ubinuclein 1 antibody, UBN1 antibody, ubn1 antibody, Ubn1 antibody

Background: UBN1 acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly. Synonyms: Monoclonal UBN1 antibody, Anti-UBN1 antibody, Ubiquitously expressed nuclear protein 1 antibody, VT antibody, VT4 antibody.