Factor VII antibody (C-Term)

Catalog No. ABIN929426

Product Details anti-Factor VII Antibody

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Factor VII antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: F7 antibody was raised in rabbit using the C terminal of F7 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

F7 Blocking Peptide, catalog no. 33R-1026, is also available for use as a blocking control in assays to test for specificity of this F7 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Alternative Name: F7 (F7 Products)

Synonyms: F7 antibody, wu:fb59f04 antibody, zgc:109870 antibody, SPCA antibody, AI114908 antibody, ATIII antibody, At-3 antibody, At3 antibody, LOC100223776 antibody, AI132620 antibody, Cf7 antibody, FVII antibody, mfVII antibody, f7 antibody, coagulation factor VII antibody, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 antibody, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog antibody, F7 antibody, f7 antibody, Serpinc1 antibody, CpipJ_CPIJ009142 antibody, CpipJ_CPIJ010295 antibody, CpipJ_CPIJ020127 antibody, fa7 antibody, f7.S antibody

Background: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. Synonyms: Polyclonal F7 antibody, Anti-F7 antibody, coagulation factor VII, serum prothrombin conversion accelerator antibody.

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling