ADRA1B antibody (C-Term)

Catalog No. ABIN929407

Product Details anti-ADRA1B Antibody

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRA1B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: ADRA1 B antibody was raised in rabbit using the C terminal of ADRA1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

ADRA1B Blocking Peptide, catalog no. 33R-10230, is also available for use as a blocking control in assays to test for specificity of this ADRA1B antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ADRA1B

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Alternative Name: ADRA1B (ADRA1B Products)

Synonyms: LOC100136712 antibody, [a]1b antibody, ADRA1 antibody, ALPHA1BAR antibody, RDC5 antibody, alpha-1B adrenoceptor antibody, adrenoceptor alpha 1B antibody, adrenergic receptor, alpha 1b antibody, LOC100136712 antibody, ADRA1B antibody, Adra1b antibody

Background: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. Synonyms: Polyclonal ADRA1B antibody, Anti-ADRA1B antibody, adrenergic, alpha-1B-, receptor antibody, ADRA1 antibody, ALPHA1BAR antibody.

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process