ADD3 antibody (C-Term)

Catalog No. ABIN929397

Product Details anti-ADD3 Antibody

Target: ADD3 (Adducin 3 (Gamma) (ADD3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADD3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: ADD3 antibody was raised in rabbit using the C terminal of ADD3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

ADD3 Blocking Peptide, catalog no. 33R-1908, is also available for use as a blocking control in assays to test for specificity of this ADD3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ADD3

Target: ADD3 (Adducin 3 (Gamma) (ADD3))

Alternative Name: ADD3 (ADD3 Products)

Synonyms: gamma-adducin antibody, add3 antibody, MGC89418 antibody, ADD3 antibody, DKFZp459E0630 antibody, ADDL antibody, AI463285 antibody, R75380 antibody, adducin 3 (gamma) antibody, adducin 3 antibody, adducin 3 L homeolog antibody, ADD3 antibody, add3 antibody, add3.L antibody, Add3 antibody

Background: Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues.sPolymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. Synonyms: Polyclonal ADD3 antibody, Anti-ADD3 antibody, adducin 3, gamma antibody, ADDL antibody.