CERKL antibody (C-Term)

Catalog No. ABIN929363

Product Details anti-CERKL Antibody

Target: CERKL (Ceramide Kinase-Like (CERKL))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CERKL antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: CERKL antibody was raised in rabbit using the C terminal of CERKL as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CERKL Blocking Peptide, catalog no. 33R-1539, is also available for use as a blocking control in assays to test for specificity of this CERKL antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CERKL

Target: CERKL (Ceramide Kinase-Like (CERKL))

Alternative Name: CERKL (CERKL Products)

Synonyms: RGD1561057 antibody, Gm1958 antibody, Rp26 antibody, GB19002 antibody, RP26 antibody, zgc:162213 antibody, ceramide kinase like antibody, ceramide kinase-like antibody, ceramide kinase antibody, CERKL antibody, Cerkl antibody, LOC408315 antibody, CERK antibody, LOC100566923 antibody, LOC100645684 antibody, cerkl antibody

Background: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts. Synonyms: Polyclonal CERKL antibody, Anti-CERKL antibody, ceramide kinase-like antibody, RP26 antibody.