HNMT antibody (N-Term)

Catalog No. ABIN929287

Product Details anti-HNMT Antibody

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNMT antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: HNMT antibody was raised in rabbit using the N terminal of HNMT as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HNMT Blocking Peptide, catalog no. 33R-7107, is also available for use as a blocking control in assays to test for specificity of this HNMT antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for HNMT

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Alternative Name: HNMT (HNMT Products)

Synonyms: HMT antibody, HNMT-S1 antibody, HNMT-S2 antibody, hmt antibody, hnmt antibody, hnmt-s1 antibody, hnmt-s2 antibody, zgc:100917 antibody, HNMT antibody, 1500031F01Rik antibody, AI788969 antibody, HMT A antibody, hnmt-a antibody, hnmt-b antibody, histamine N-methyltransferase antibody, histamine N-methyltransferase S homeolog antibody, histamine N-methyltransferase-like antibody, histamine N-methyltransferase L homeolog antibody, HNMT antibody, hnmt.S antibody, hnmt antibody, Hnmt antibody, LOC100228106 antibody, hnmt.L antibody

Background: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. Synonyms: Polyclonal HNMT antibody, Anti-HNMT antibody, histamine N-methyltransferase antibody, HMT antibody, HNMT-S1 antibody, HNMT-S2 antibody.