ATF5 antibody (Middle Region)

Catalog No. ABIN929026

Product Details anti-ATF5 Antibody

Target: ATF5 (Activating Transcription Factor 5 (ATF5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF5 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Frog, Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: ATF5 antibody was raised in rabbit using the middle region of ATF5 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

ATF5 Blocking Peptide, catalog no. 33R-5281, is also available for use as a blocking control in assays to test for specificity of this ATF5 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ATF5

Target: ATF5 (Activating Transcription Factor 5 (ATF5))

Alternative Name: ATF5 (ATF5 Products)

Synonyms: ATF5 antibody, atfx antibody, hmfn0395 antibody, ATFX antibody, HMFN0395 antibody, AFTA antibody, Atf7 antibody, Atfx antibody, ODA-10 antibody, atf5 antibody, activating transcription factor 5 antibody, activating transcription factor 5, gene 2 S homeolog antibody, ATF5 antibody, atf5 antibody, Atf5 antibody, atf5.2.S antibody

Background: ATF5 belongs to the bZIP family. It is transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Loss of ATF5 is associated with hepatocellular carcinoma. Synonyms: Polyclonal ATF5 antibody, Anti-ATF5 antibody, activating transcription factor 5 antibody, ATFX antibody, FLJ34666 antibody, HMFN0395 antibody.

Pathways: Myometrial Relaxation and Contraction