PNRC2 antibody (N-Term)

Catalog No. ABIN928925

Product Details anti-PNRC2 Antibody

Target: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Binding Specificity: N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNRC2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus)

Purification: Purified

Immunogen: Pnrc2 antibody was raised in rabbit using the N terminal of Pnrc2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Pnrc2 Blocking Peptide, catalog no. 33R-6028, is also available for use as a blocking control in assays to test for specificity of this Pnrc2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for PNRC2

Target: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Alternative Name: Pnrc2 (PNRC2 Products)

Synonyms: 0610011E17Rik antibody, D4Bwg0593e antibody, wu:cegs2777 antibody, wu:fb51a04 antibody, wu:fb81a06 antibody, wu:fd19g06 antibody, proline rich nuclear receptor coactivator 2 antibody, proline-rich nuclear receptor coactivator 2 antibody, PNRC2 antibody, Pnrc2 antibody, pnrc2 antibody

Background: Pnrc2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. It may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. It is required for UPF1/RENT1 localization to the P-body.It also acts as a nuclear receptor coactivator. It may play a role in controlling the energy balance between energy storage and energy expenditure. Synonyms: Polyclonal Pnrc2 antibody, Anti-Pnrc2 antibody, Pproline-rich nuclear receptor coactivator 2 antibody, MGC93828 antibody, Pnrc2 antibody.