RAD21 antibody (N-Term)

Catalog No. ABIN928887

Product Details anti-RAD21 Antibody

Target: RAD21 (RAD21 Homolog (RAD21))

Binding Specificity: N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD21 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus)

Purification: Purified

Immunogen: Rad21 antibody was raised in rabbit using the N terminal of Rad21 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Rad21 Blocking Peptide, catalog no. 33R-2307, is also available for use as a blocking control in assays to test for specificity of this Rad21 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Alternative Name: Rad21 (RAD21 Products)

Synonyms: rad21 antibody, wu:fb55d02 antibody, wu:fb93f04 antibody, CDLS4 antibody, HR21 antibody, HRAD21 antibody, MCD1 antibody, NXP1 antibody, SCC1 antibody, hHR21 antibody, mKIAA0078 antibody, hr21 antibody, mcd1 antibody, nxp-1 antibody, nxp1 antibody, scc1 antibody, xrad21 antibody, RAD21 cohesin complex component antibody, RAD21 cohesin complex component a antibody, RAD21 cohesin complex component L homeolog antibody, RAD21 cohesin complex component S homeolog antibody, R-spondin 2 antibody, RAD21 antibody, rad21a antibody, rad21.L antibody, Rad21 antibody, rad21.S antibody, RSPO2 antibody

Background: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene  involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a  nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid  cohesion in mitotic cells. Synonyms: Polyclonal Rad21 antibody, Anti-Rad21 antibody, RAD21 homolog, S. pombe antibody, MGC116373 antibody, Rad21 antibody.

Pathways: Positive Regulation of Endopeptidase Activity