NXT1 antibody (N-Term)

Catalog No. ABIN928749

Product Details anti-NXT1 Antibody

Target: NXT1 (NTF2-Related Export Protein 1 (NXT1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NXT1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: NXT1 antibody was raised in rabbit using the N terminal of NXT1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

NXT1 Blocking Peptide, catalog no. 33R-3600, is also available for use as a blocking control in assays to test for specificity of this NXT1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for NXT1

Target: NXT1 (NTF2-Related Export Protein 1 (NXT1))

Alternative Name: NXT1 (NXT1 Products)

Background: The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. Synonyms: Polyclonal NXT1 antibody, Anti-NXT1 antibody, NTF2-like export factor 1 antibody, MTR2 antibody, P15 antibody.