FBXO31 antibody (Middle Region)
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- Target See all FBXO31 Antibodies
- FBXO31 (F-Box Protein 31 (FBXO31))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FBXO31 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogen
- FBXO31 antibody was raised in rabbit using the middle region of FBXO31 as the immunogen
- Top Product
- Discover our top product FBXO31 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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FBXO31 Blocking Peptide, catalog no. 33R-7570, is also available for use as a blocking control in assays to test for specificity of this FBXO31 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- FBXO31 (F-Box Protein 31 (FBXO31))
- Alternative Name
- FBXO31 (FBXO31 Products)
- Synonyms
- 1110003O08Rik antibody, 2310046N15Rik antibody, Fbx14 antibody, Fbxo14 antibody, FBX14 antibody, FBXO14 antibody, Fbx31 antibody, pp2386 antibody, RGD1561069 antibody, fbx14 antibody, fbx31 antibody, fbxo14 antibody, fbxo31 antibody, F-box protein 31 antibody, F-box protein 31 S homeolog antibody, F-box protein 31 L homeolog antibody, Fbxo31 antibody, FBXO31 antibody, fbxo31 antibody, fbxo31.S antibody, fbxo31.L antibody
- Background
- FBXO31 is the component of some SCF protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor. Synonyms: Polyclonal FBXO31 antibody, Anti-FBXO31 antibody, F-box protein 31 antibody, DKFZP434B027 antibody, DKFZp434J1815 antibody, FBX14 antibody, FBXO14 antibody, FLJ22477 antibody, Fbx31 antibody, MGC15419 antibody, MGC9527 antibody, pp2386 antibody.
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