SPA17 antibody (N-Term)

Catalog No. ABIN928702

Product Details anti-SPA17 Antibody

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPA17 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: SPA17 antibody was raised in rabbit using the N terminal of SPA17 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SPA17 Blocking Peptide, catalog no. 33R-6445, is also available for use as a blocking control in assays to test for specificity of this SPA17 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SPA17

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Alternative Name: SPA17 (SPA17 Products)

Synonyms: spa17 antibody, MGC89454 antibody, SPA17 antibody, CT22 antibody, SP17 antibody, SP17-1 antibody, Sp17 antibody, sperm autoantigenic protein 17 antibody, sperm autoantigenic protein 17 L homeolog antibody, spa17 antibody, SPA17 antibody, spa17.L antibody, Spa17 antibody

Background: This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22. Synonyms: Polyclonal SPA17 antibody, Anti-SPA17 antibody, sperm autoantigenic protein 17 antibody, SP17 antibody, SP17-1 antibody.