HYAL1 antibody (N-Term)

Catalog No. ABIN928458

Product Details anti-HYAL1 Antibody

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus), Mouse (Murine), Pig (Porcine), Cow (Bovine)

Purification: Purified

Immunogen: HYAL1 antibody was raised in rabbit using the N terminal of HYAL1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

HYAL1 Blocking Peptide, catalog no. 33R-9982, is also available for use as a blocking control in assays to test for specificity of this HYAL1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for HYAL1

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Alternative Name: HYAL1 (HYAL1 Products)

Synonyms: HYAL-1 antibody, LUCA1 antibody, NAT6 antibody, Hya1 antibody, Hyal-1 antibody, hyaluronoglucosaminidase 1 antibody, HYAL1 antibody, Hyal1 antibody

Background: HYAL1 is a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. HYAL1 is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Synonyms: Polyclonal HYAL1 antibody, Anti-HYAL1 antibody, hyaluronoglucosaminidase 1 antibody, HYAL-1 antibody, LUCA1 antibody, MGC45987 antibody, NAT6 antibody.

Pathways: Glycosaminoglycan Metabolic Process