SPRY2 antibody (N-Term)

Catalog No. ABIN928374

Product Details anti-SPRY2 Antibody

Target: SPRY2 (Sprouty Homolog 2 (SPRY2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRY2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)

Purification: Purified

Immunogen: SPRY2 antibody was raised in rabbit using the N terminal of SPRY2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SPRY2 Blocking Peptide, catalog no. 33R-5896, is also available for use as a blocking control in assays to test for specificity of this SPRY2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SPRY2

Target: SPRY2 (Sprouty Homolog 2 (SPRY2))

Alternative Name: SPRY2 (SPRY2 Products)

Synonyms: wu:fk66h11 antibody, wu:fk93e11 antibody, zgc:110440 antibody, hspry2 antibody, xspry2 antibody, sprouty2 antibody, Xsprouty2 antibody, sprouty-2 antibody, Xtsprouty2 antibody, hSPRY2 antibody, sprouty RTK signaling antagonist 2 antibody, sprouty RTK signaling antagonist 2 S homeolog antibody, sprouty homolog 2 (Drosophila) antibody, spry2 antibody, SPRY2 antibody, spry2.S antibody, Spry2 antibody

Background: SPRY2 is a protein belonging to the sprouty family. It contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. SPRY2 is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. Synonyms: Polyclonal SPRY2 antibody, Anti-SPRY2 antibody, sprouty homolog 2, Drosophila antibody, MGC23039 antibody, hSPRY2 antibody.

Pathways: EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation